Gyneocology
ashraf saber mashhad taraqi; Najmeh Tehranian; Somayeh Yousefi; Anoshrvan Kazemnejad
Volume 26, Issue 3 , September and October 2019, , Pages 337-343
Abstract
Background and Aims: one of the hormones that appears to play an important role in regulating body growth is ghrelin. This study aimed to determine the association between Maternal serum ghrelin level and neonatal anthropometric indicators at birth.Materials & Methods: In this cohort study, 35 eligible ...
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Background and Aims: one of the hormones that appears to play an important role in regulating body growth is ghrelin. This study aimed to determine the association between Maternal serum ghrelin level and neonatal anthropometric indicators at birth.Materials & Methods: In this cohort study, 35 eligible pregnant women in their first trimester that were allocated by Using Convenience sampling were divided and matched in terms of BMI before pregnancy into normal and higher than normal BMI groups A ( n=14) and B ( n=21). Serum ghrelin level was measured during 6-12 and 15-20 weeks of gestation using ELISA method.Results: Mean non-fasting serum gherlin level (first and second trimesters) had not significant deference between two groups (p1=0.93, p2=0.76, in first and second trimester, respectively). Also there is a ascending increase in mean serum ghrelin level with increasing gestational age from the first to the second trimesters in both groups but was not significant (pa=0.15, pb=0.24, in A and B group, respectively). No significant correlations were detected between non-fasting serum gherlin level (first and second trimesters) and neonatal anthropometric indicators.Conclusion: The lack of any direct relationship between Maternal serum ghrelin level and neonatal anthropometric indicators does not support the hypothesis that ghrelin has major role in foetal growth